Where Negative Equity is Concentrated

first_img Servicers Navigate the Post-Pandemic World 2 days ago Governmental Measures Target Expanded Access to Affordable Housing 2 days ago Share Save  Print This Post March 12, 2020 1,845 Views Subscribe Previous: Regulators Responding to Coronavirus Spread Next: USFN Cancels Industry Events Data Provider Black Knight to Acquire Top of Mind 2 days ago The Best Markets For Residential Property Investors 2 days ago in Daily Dose, Featured, Loss Mitigation, Market Studies, News About Author: Seth Welborn Demand Propels Home Prices Upward 2 days ago Home / Daily Dose / Where Negative Equity is Concentrated Demand Propels Home Prices Upward 2 days agocenter_img Seth Welborn is a Reporter for DS News and MReport. A graduate of Harding University, he has covered numerous topics across the real estate and default servicing industries. Additionally, he has written B2B marketing copy for Dallas-based companies such as AT&T. An East Texas Native, he also works part-time as a photographer. Related Articles The Best Markets For Residential Property Investors 2 days ago The Week Ahead: Nearing the Forbearance Exit 2 days ago Data Provider Black Knight to Acquire Top of Mind 2 days ago Servicers Navigate the Post-Pandemic World 2 days ago Where Negative Equity is Concentrated Tagged with: Equity Home Prices Negative Equity Equity Home Prices Negative Equity 2020-03-12 Seth Welborn Governmental Measures Target Expanded Access to Affordable Housing 2 days ago Sign up for DS News Daily Nationwide, the negative equity share for the fourth quarter of 2019 was 3.5% of all homes with a mortgage, the lowest share of homes with negative equity since the third quarter of 2009 according to CoreLogic’s latest Equity Report. By state, the largest negative equity share was in Louisiana, with 9.8% of mortgages with negative equity—more than twice the national average.Behind Louisiana, Connecticut (7.1%) and Illinois (7%) rounded out the top three states with the highest negative equity shares. States with high negative equity shares have experienced low home price appreciation. While Florida makes the top ten list for negative equity share, that state saw a large year-over-year decline in negative equity share, falling from 6.2% in the fourth quarter of 2018 to 4.8% in the fourth quarter of 2019.Louisiana also topped ATTOM Data Solution’s Q4 Home Equity & Underwater Reportlist of seriously underwater homes, with 16.8% seriously underwater. Louisiana was followed by Mississippi (16.0%, West Virginia (13.9%), Iowa (13.5%) and Arkansas (12.9%). Similarly, states with the lowest percentage of equity-rich properties were Louisiana (13.6% equity-rich), Oklahoma (14.9%), Illinois (15.3%), Arkansas (16.3%) and Alabama (16.5%).According to CoreLogic, the amount of equity in mortgaged real estate increased by $489 billion in the fourth quarter of 2019 from the fourth quarter of 2018, an annual increase of 5.4%. Borrower equity hit a new high in the fourth quarter of 2019, and borrowers have gained over $6 trillion in equity since the end of 2011 when equity stopped declining. Years of home price increases have led to record-levels of home equity and pick up in price gains in the fourth quarter of 2019 boosted home-equity wealth further.On the metro level, San Francisco has the largest average amount of negative equity, but the negative equity share is only 0.7%. Miami has the smallest average amount of negative equity, but has a negative equity share of 8.5%, which is more than double the national rate.Additionally, the number of underwater properties decreased by 330,000 from the fourth quarter of 2018 to the fourth quarter of 2019.last_img read more

New York’s 9/11 ‘Tribute in Light’ endangers 160,000 birds annually: Study

first_imgBird-safe Building Legislation is gaining momentum! A public hearing on the City Council’s proposed Bird-friendly Glass Bill (Int 1482-2019) is scheduled for September 10, 10am, at City Hall. More details on how you can support this bill to come! https://t.co/oXj0cUNw0Y— NYC Audubon (@NYCAudubon) August 30, 2019Up to 230,000 birds are killed each year crashing into buildings in New York City alone, according to NYC Audubon.On Tuesday, the New York City Council was set to hold a committee meeting on a bill that would require new or renovated buildings to use bird-friendly glass or glass birds can see more clearly.Copyright © 2019, ABC Radio. All rights reserved. Michael Ver Sprill/iStock(NEW YORK) — The “Tribute in Light,” New York City’s annual homage to the victims who perished in the Sept. 11, 2001, terrorist attacks, endangers an estimated 160,000 migrating birds a year, drawing them off course and trapping them in the powerful twin beams that shoot into the sky and can be seen from 60 miles away, according to avian experts.The illuminating installation on display for seven days leading up the anniversary of the hijacked airliner attacks that brought down the two World Trade Center towers, killing nearly 3,000 people, may serve as solemn beacons of remembrance for most people.But the exhibit also coincides with the annual migration of tens of thousands of birds crisscrossing the New York region — including songbirds, Canada and yellow warblers, American redstarts, sparrows and other avian species — that get confused and fly into the towers of light, circling and expending energy and threatening their lives, according to officials at New York City Audubon.Andrew Maas, a spokesman for NYC Audubon, told ABC News on Tuesday that the artificial light interferes with the birds’ natural cues to navigate. Circling within the lights can exhaust the birds and potentially lead to their demise, he noted.“We know it’s a sensitive issue,” he said, adding that NYC Audubon has worked for years with the 9/11 Memorial & Museum and the Municipal Art Society of New York, which created the exhibit, to balance protecting the birds while providing the temporary memorial.The lights also attract bats and birds of prey, including nighthawks and peregrine falcons, who feed on small birds and millions of insects drawn to the lights, The New York Times reported on Tuesday.A 2017 study published in Proceedings of the National Academy of Sciences of the United States of America, found the Tribute in Light affected 1.1 million migrating birds observed by scientists during the annual exhibit between 2008 and 2016, or about 160,000 birds a year.“Nocturnally migrating birds are particularly susceptible to artificial light because of adaptations and requirements for navigating and orienting in darkness,” according to the study by researchers from NYC Audubon, Oxford University and the Cornell Lab of Ornithology.The seven-year study found that while the urban light installation “altered multiple behaviors of nocturnally migrating birds,” it also discovered that the birds disperse and return to their migratory patterns when the lights are turned off.Every year, a team of volunteers from NYC Audubon monitor the birds circling in the beams and when the number reaches 1,000, volunteers ask that the lights be turned off for about 20 minutes to free the birds from the seemingly magnetic hold of the lights.While the Tribute in Light is a temporary hazard to migrating birds, skyscrapers with reflective windows are a permanent threat to feathered flocks that fly around New York City.last_img read more

Trophodynamics of Protomyctophum (Myctophidae) in the Scotia Sea (Southern Ocean)

first_imgThis study investigated spatial and temporal patterns in distribution, population structure and diet of Bolin’s lanternfish Protomyctophum bolini, Tenison’s lanternfish Protomyctophum tenisoni and gaptooth lanternfish Protomyctophum choriodon in the Scotia Sea using data collected by midwater trawl during spring, summer and autumn. Protomyctophum bolini was the most abundant species of the genus encountered throughout the Scotia Sea with the greatest concentrations occurring around the Antarctic Polar Front (APF). This species had a life cycle of 2+ years, but spatial differences in population structure were apparent as the I-group was absent from all regions south of the APF, suggesting that the species does not recruit in the Scotia Sea. Protomyctophum tenisoni occurred mostly in waters characteristic of the APF and was absent from the southern Scotia Sea. It had a limited size range, but there was clear size-related sexual dimorphism with males significantly larger than females. The species had a life cycle of c. 2 years, but the I-group (c. 1 year old, 1 November to 31 October the next year) occurred only in regions close to the APF suggesting that recruitment is restricted to these waters. A seasonal southward migration for P. choriodon is likely as the species occurred mostly to the south-west of South Georgia in summer, but extended to the sea-ice sectors in autumn. Protomyctophum choriodon had a life cycle of 4+ years in the Scotia Sea and the population was dominated by age classes >3 years old. Larval stages were absent during the surveys for all species. Diurnal variations in vertical distribution were apparent for all three species. Interspecific variations in diet were evident, but all species were primarily copepod feeders, with Metridia spp., Rhincalanus gigas and Calanus simillimus generally dominating their diet. Small euphausiids, principally Thysanoessa spp., were also an important component of their diets, particularly for P. choriodon which had the largest body size. The spatial and temporal variations in diet for both P. bolini and P. tenisoni were broadly consistent with underlying abundance patterns within the mesozooplankton community.last_img read more

Oxford Playhouse begins major refurbishment

first_imgThe Oxford Playhouse Theatre has launched a project to significantly update its facilities. The refurbishment will cost £700,000 of which over half will come from the Arts Council’s Small Capital Fund. The upstairs circle bar will be moved to the centre of the circle to facilitate the movement of people. Interim Director, Polly Cole, commented, “it makes more sense for it to be in the centre because you come up both sides. It will also be larger so we can serve more people.”There will also be a major change to the auditorium, last updated in 1996. Cole observed that at the moment “the seating is worn, the fixtures are collapsing… some of the seats collapse so we have to check them between shows to make sure they are fit for purpose. The carpet is horrendously worn. It is currently held together with gaffer tape.”Other modernizations will include replacing the air conditioning system, refurbishing the downstairs foyer bar and replacing leather stools with fabric. However, Cole was keen to assure regular theatregoers that “the look of it [the theatre] will be very similar, it will change slightly.”It is thought that 150,000 people go the Playhouse every year. The Playhouse also has a strong relation with student drama, offering two performance slots a term for student productions.The work will take place for one month every summer for the next three years. The theatre is currently closed until the 18th of August.last_img read more

AG Curtis Hill: Cannabidiol (CBD)Products Are Illegal In Indiana

first_imgAttorney General Curtis Hill today released the following statement in conjunction with the issuance of an advisory opinion from his office regarding the legality of cannabidiol products.“Over recent weeks, I’ve worked with my staff to develop an advisory opinion regarding the status under Indiana law of the chemical compound cannabidiol – better known as ‘CBD.’ Cannabidiol is one of the most prevalent chemical compounds in the cannabis plant, otherwise known as marijuana.“This issue has drawn public attention this year following law-enforcement actions against Indiana stores marketing and selling ‘CBD oil,’ a substance delivered to consumers in dropper bottles, sprays or mists – all generally to be taken orally.“My task at this juncture is not to express my personal view of what I believe the law ought to stipulate. My task, rather, is to help provide clarity regarding what the law already says as written.“There is no doubt, as a matter of legal interpretation, that products or substances marketed generally for human consumption or ingestion, and containing cannabidiol, remain unlawful in Indiana as well as under federal law.“Indiana law does allow for a limited and focused exception created by House Enrolled Act 1148, signed earlier this year, aimed at individuals battling treatment-resistant epilepsy. This legislation pertains specifically to individuals properly added to the newly created Indiana State Department of Health Cannabidiol Registry.“Cannabidiol is classified under state and federal law as a Schedule I controlled substance because marijuana (Cannabis sativa) is a Schedule I controlled substance. State and federal laws that place cannabidiol in the category of a Schedule I controlled substance do not hinge on the degree or prevalence of pharmacological effects of a substance on a person.“The manufacture, possession, use and sale of cannabidiol – and substances, food products or edible oils containing cannabidiol – are unlawful under both Indiana and federal law. Any individual possessing a substance containing cannabidiol – or anything packaged as such – in plain view of a law enforcement officer is subject to having that property seized. Only upon showing that one meets the limited conditions under Indiana law could one expect to avoid being prosecuted under Indiana law. Further, no one in Indiana is authorized to sell cannabidiol or any substance containing cannabidiol under state or federal law.”FacebookTwitterCopy LinkEmailSharelast_img read more

Press release: Appointment of Peter Schofield as Permanent Secretary at the Department for Work and Pensions

first_img Scotland (local media enquiries) 0131 310 1122 Press Office The Rt Hon Esther McVey, Secretary of State for Work and Pensions, said: Twitter – www.twitter.com/dwppressoffice Facebook – www.facebook.com/dwp LinkedIn – www.linkedin.com/company/dwp YouTube – www.youtube.com/dwp England and Wales (local media enquiries) 029 20 586 then 097 or 098 or 099 London Press Office (national media and London area enquiries only – not questions about personal claims) 020 3267 5144 Peter Schofield said: Out-of-hours (journalists only) 07623 928 975 I look forward to welcoming Peter Schofield as DWP’s new Permanent Secretary and to working with him on ensuring we continue to deliver a welfare system that supports people when they need it, and helps them fulfil their potential – no matter who they are or where they come from. Caxton HouseTothill StreetLondonSW1H 9NA This appointment has been agreed by the Prime Minister, and follows an external recruitment competition.Peter Schofield has held the role of Finance Director General in DWP since July 2016.Arrangements for appointing a successor to fill his previous role will be announced in due course.Contact Press Office DWP is a remarkable organisation – in scale, reach, ability to deliver change, and the motivation and pride of my 80,000 colleagues providing high quality support to over 22 million citizens. It is a huge honour to be given the opportunity to lead DWP and support the new Secretary of State and her ministerial team, and to build on Robert’s outstanding leadership over the last 7 years. I can’t wait to start. I am delighted to announce the appointment of Peter Schofield as the new Permanent Secretary for the Department for Work and Pensions. Peter has done an excellent job as Finance Director General at the department and will bring to his new role a wealth of relevant knowledge and experience. I look forward to working with him as he starts his work delivering DWP’s important mission. I would also like to take this opportunity to thank Sir Robert Devereux for his excellent leadership of the department during his time as Permanent Secretary. Follow DWP on: The Cabinet Secretary, with the agreement of the Prime Minister, has today announced that Peter Schofield, currently Director General of Finance at the Department for Work and Pensions (DWP), has been appointed as the new Permanent Secretary on Sir Robert Devereux’s retirement later this month.Welcoming Peter Schofield’s appointment Sir Jeremy Heywood said:last_img read more

News story: Webinar – 17 April – How SMEs can supply through Crown Marketplace

first_imgMatt Denham is the man leading the build of the Crown Marketplace; a platform through which government is set to buy all its common goods and services, and which is being developed with an emphasis on making the procurement process SME friendly. In this webinar, Matt will outline the timetable for launch of the Crown Marketplace and how small businesses can best prepare to make the most of a multi million pound opportunity to sell to government.Click here to register.last_img

News story: Engineering in the spotlight for 2018 as government launches campaign to inspire the next generation

first_imgA pioneering campaign to transform the way young people see engineering and boost numbers entering the profession has been launched today (15 January 2018).Ministers from across government are joining forces with engineers, industry experts and hundreds of businesses to change perceptions around engineering – and highlight the scale of opportunity that careers in the industry hold for young people in the UK.2018 is officially the Year of Engineering and will see a national drive in all corners of the country to inspire the young people who will shape our future.Engineering is one of the most productive sectors in the UK, but a shortfall of 20,000 engineering graduates every year is damaging growth. There is also widespread misunderstanding of engineering among young people and their parents and a lack of diversity in the sector – the workforce is 91% male and 94% white.Year of EngineeringThe new campaign is aimed at filling those gaps and changing misconceptions, and will see government and around 1,000 partners deliver a million inspiring experiences of engineering for young people, parents and teachers.Activities will include: All week, engineers, businesses, schools and universities will be marking the launch of the campaign by celebrating the positive impact of engineering. Events include: Crossrail Chair Sir Terry Morgan said: News desk enquiries To find out more about the Year of Engineering: Skills Minister, Anne Milton said: Engineers – whether they are working on cutting-edge technology in aerospace, energy or artificial intelligence – are vital to the lifeblood of our economy. We want to show young people and their parents the immense creativity, opportunity and value of the profession. By bringing them face to face with engineering role models and achievements we can send a clear message that engineering careers are a chance for all young people, regardless of gender, ethnicity or social background, to shape the future of this country and have a real impact on the lives of those around them. a Siemens See Women roadshow aimed at inspiring women, including more black, Asian and minority ethnic girls, into pursuing STEM careers a brand new children’s book on engineering from Usborne the Science Museum and London Transport Museum will be capturing children’s imaginations with interactive exhibitions schools will get the chance to go behind the scenes at Airbus to meet engineers working on the Mars Rover Thales in the UK will be inspiring inventors of the future with robot clubs in primary schools Sir James Dyson, through the Dyson Institute, the James Dyson Foundation and the James Dyson Award, will continue to invest in inspiring young engineers by providing opportunities to apply engineering principles to projects that solve real world problems Mark Richardson, Ocado Chief Operating Officer, said: Out of hours media enquiries 020 7944 4292center_img Secretary of State for Transport Chris Grayling said: Media enquiries 020 7944 3021 students in Bolton using engineering to tackle real life challenges for people with disabilities with charity Remap pupils at a London school taking on a cybersecurity competition engineers, STEM ambassadors and schoolchildren will gather for the unveiling of Tim Peake’s spacecraft at the National Railway Museum in York Ocado in Birmingham will give schoolchildren the chance to see robots in action The Year of Engineering will be a fantastic opportunity to inspire others to take a fresh look at engineering and show the range of opportunities there are for training and jobs in this sector. We look forward to showcasing the role engineers have played in creating such an amazing project before the Elizabeth line opens to passengers at the end of 2018. I want to see everyone whatever their background, wherever they live to have a chance to get a rewarding career or job in engineering whether they come via a technical or academic route. The Year of Engineering gives us a great opportunity to work together with business to inspire a new generation of world class engineers. We want to build the science, technology, engineering and mathematics skills that we need for a growing economy, as highlighted in the government’s Industrial Strategy. visit the website follow the campaign on Twitter follow the campaign on Instagram Encouraging more young people to enter the engineering profession is essential to ensure the growth and development of new technologies and businesses in the UK. At Ocado we build the world’s most advanced automated warehouses for online grocery, and we hope our involvement in this campaign will offer young people from diverse backgrounds a real insight into the exciting and rewarding life of an engineer. Switchboard 0300 330 3000last_img read more

Check Out These Gorgeous Photos From Lettuce’s Show At Charleston, SC’s Music Farm

first_imgCurrently, the funk gurus of Lettuce are at the tail end of their fall 2018 Wavelength tour, which started on September 20th and spans until this weekend with a run across the Midwest. Over the weekend, the fan-favorite funk act was in the South, with a festival performance at Pittsboro, NC’s Fall Shakori Hills Grassroots Festival on Saturday ahead of a headlining Sunday night show at Charleston, SC’s Music Farm.For the Charleston show, the band laid out an exceptional one-set performance, highlighting the group’s increasing desire to extend and savor psychedelic jams. Opening with “Blast Off”, off 2008’s Rage!, the group worked through a number of their classic tunes for the Charleston crowd. The opening “Blast Off” saw one of the longest jams of the night, with the rendition clocking in at 11 minutes. However, another major highlight of the evening was at 17-minute take on “Yakatori” toward the tail end of the show. Other highlights included an electrifying take on “Get Greasy” off 2015’s Crush and a standout rendition of “House”, a new song debuted last fall that has been solidifying itself within the Lettuce catalog.You can check out a gorgeous gallery of photos from Lettuce’s performance at Charleston, South Carolina’s Music Farm below, courtesy of Ellison White.Setlist: Lettuce | Music Farm | Charleston, SC | 10/7/2018Set One: Blast Off, KHRU, Lettsanity, Let The Good Times Roll, Get Greasy, Purple Cabbage, Ready To Live, Yakatori, Breakout, House, Do It Like You DoLettuce | Music Farm | Charleston, SC | 10/7/2018 | Photo: Ellison White Photo: Ellison White Photo: Ellison White Photo: Ellison Whitecenter_img Photo: Ellison White Load remaining imageslast_img read more

A transplant makes history

first_imgAs Harvard celebrates its 375th anniversary, the Gazette is examining key moments and developments over the University’s broad and compelling history.In late 1954, Richard Herrick was dying. Just 23 years old, he had been discharged from the Coast Guard months earlier and had come home to Massachusetts to reconnect with his family, which included his twin brother, Ronald.But the joy of his reunion was tempered by Herrick’s diagnosis of kidney disease, which at the time was often a death sentence. By October, he was a patient at the Public Health Service Hospital in Brighton, Mass. His health was worsening.His family kept a vigil by his bedside, but had been told that his kidneys were failing and that there was little hope of a cure. Yet Herrick’s doctor recalled that not far away, at the Peter Bent Brigham Hospital and Harvard Medical School (HMS), some doctors and scientists were working on the problem. They were devising ways to transplant healthy kidneys into those whose organs had failed, and they were looking for twins to attempt the first operation.The small group was viewed with skepticism by the medical establishment, with one physician dubbing them “a bunch of fools” for their efforts. There were valid grounds for skepticism. After all, even if they could surmount the technical hurdles of the transplant — severing and reattaching blood vessels and other critical connections — the body’s rejection of foreign tissue was poorly understood and could not be overcome.But the group of “fools,” led by a young surgeon and Harvard Medical School professor named Joseph Murray, felt strongly that they — and their dying patients — had nothing to lose and much to gain.“If you’re going to worry about what people say, you’re never going to make any progress,” Murray said during a recent interview at his home in Wellesley Hills, Mass.The group’s perseverance and skill would bear fruit just before Christmas that year when they performed the world’s first successful organ transplant, between Richard and Ronald. At 11:15 a.m. on Dec. 23, their work not only gave Richard a new lease on life, it ushered in the era of organ transplantation, giving hope to thousands of patients each year whose own organs are failing. Richard Herrick lived eight more years.Today, roughly 17,000 Americans undergo kidney transplantation annually, according to statistics from the National Institutes of Health. Nearly all of them — better than 95 percent —survive the first year after surgery, and more than 80 percent are still alive five years later.Not only have the number of kidney transplants skyrocketed, but physicians building on Murray’s and his colleagues’ work have pioneered the transplantation of many kinds of organs. Between 1988 and 2011, more than half a million organs were transplanted in this country alone, according to the U.S. Department of Health and Human Services (HHS). (At the same time, more than 121,000 people — including more than 600 children under age 5 — are waiting for organs in this country, according to HHS statistics.)“It opened up a whole new concept of treatment, by substituting a failed organ with a healthy organ from someone else,” said Nicholas Tilney, the Francis D. Moore Distinguished Professor of Surgery at HMS and the Brigham, and author of the book “Transplant: From Myth to Reality (2003).” “When I got here in 1964, the early mortality rate following transplantation was as high as 50 percent. By the end of the year, there were virtually no survivors. Now, if someone dies, it’s a cause of great angst.”As Harvard looks back at the 375 years since its founding, Murray’s work on organ transplantation stands out as a scientific and medical milestone, one that netted him the 1990 Nobel Prize in physiology or medicine. It also illustrates the potential impact of teaching and research at Harvard, and the potent partnership with the research, teaching, and patient care going on at its affiliated hospitals.Murray’s milestone is just one in a long line of critical advances pioneered at Harvard and its affiliated institutions, from the first use of anesthesia at Massachusetts General Hospital in 1846, to the development of the computer by Howard Aiken in 1944, to the breakthrough by John Enders in 1948 that allowed the world to rid itself of polio, to more recent milestones, such as physicist Lene Hau stopping light in its tracks in 2005, and Harvard astrophysicists discovering planets orbiting other suns and divining that the universe is not only expanding, it is accelerating.During this key period in kidney transplantation, Murray divided his time between the Surgical Research Laboratory at Harvard Medical School, where he worked out techniques used in that and subsequent operations, and the Peter Bent Brigham Hospital — today Brigham and Women’s Hospital. At the Brigham, Murray treated patients whose deaths he would work to stop and whose courage at undertaking risky transplant surgery paved the way for the lives routinely saved by such procedures today.“I had no idea of the worldwide influence of it. It expanded to other organs, multiple organs,” Murray said.Murray, today professor of surgery emeritus at HMS, gained his first experience in tissue transplantation during World War II. Fresh out of Harvard Medical School, he was drafted and spent the war at Valley Forge General Hospital in Pennsylvania. Among his duties was grafting skin on the many burn victims who passed through his ward, an experience that got him thinking about tissue rejection.After the war, Murray returned to Harvard and the Brigham. He worked with physicians who had already begun kidney transplantation experiments and who relied on the critical support of Physician-in-Chief George Thorn, who had established a kidney transplantation program.“There was a very enthusiastic chief of surgery — nobody else was doing it — and they pushed and pushed and pushed,” said Tilney, who took over Murray’s lab after his retirement. “It was the right people in the right place at the right time.”By 1954, the work in the Surgical Research Lab had paid off. Murray felt sure they could technically perform the surgery. The rejection issue still stood in the way, but drawing on experience from skin graft surgery, where it had been shown that tissue from identical twins was not rejected, he thought that transplanting kidneys between twins should work.Though Murray and the other doctors involved had prepared extensively for the procedure, Murray said that he approached the operation as he would any other.  He once told a grandchild who asked how he got the Nobel that he didn’t work to get the prize, he just did what he thought best for his patients.After the operation, Murray’s work on transplantation continued. Despite his success with the Herricks, the problem of rejection generally still presented a high hurdle.In the years that followed, Murray used first X-rays and then drugs to suppress the immune system and keep the body from rejecting the grafted tissue, but there were few successes. Through those dark years, he and his colleagues pressed on, inspired by the dying patients who volunteered for surgery in hopes that, even if they didn’t make it, enough could be learned that success would come one day.“We were trying. In spite of several failures, we felt we were getting close,” Murray said. “It’s difficult to translate the optimism of the Brigham staff and hospital. The administration really backed us.”Finally, in 1962, in collaboration with scientists from the drug company Burroughs-Wellcome, Murray tried a drug, Imuran, on 23-year-old Mel Doucette, who had received a kidney from an unrelated cadaver donor. The success of that operation and the anti-rejection drug cleared the final hurdle to widespread organ transplantation between unrelated donors, and set the stage for the many refinements and breakthroughs by others in the years to come.Murray’s legacy didn’t end with his retirement in 1986. The Brigham continues to be a center for transplant surgery, with pioneering work in face transplantation being done today by a team led by Assistant Professor of Surgery Bohdan Pomahac, director of plastic surgery transplantation at the Brigham, giving a new lease on life to people horribly disfigured by accident.“He’s taken it far beyond anything anybody had dreamed of,” Murray said.last_img read more